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C/EBPα and DEK coordinately regulate myeloid differentiation
The transcription factor C/EBPα is a critical mediator of myeloid differentiation and is often functionally impaired in acute myeloid leukemia. Recent studies have suggested that oncogenic FLT3 activity disrupts wild-type C/EBPα function via phosphorylation on serine 21 (S21). Despite the apparent r...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society of Hematology
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367892/ https://ncbi.nlm.nih.gov/pubmed/22474248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-383083 |
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