Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling

Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in part, to be induced by phosphate imbalance. T...

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Publicado no:Sci Rep
Main Authors: Willems, Brecht A., Furmanik, Malgorzata, Caron, Marjolein M. J., Chatrou, Martijn L. L., Kusters, Dennis H. M., Welting, Tim J. M., Stock, Michael, Rafael, Marta S., Viegas, Carla S. B., Simes, Dina C., Vermeer, Cees, Reutelingsperger, Chris P. M., Schurgers, Leon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862840/
https://ncbi.nlm.nih.gov/pubmed/29563538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23353-y
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