Gla-Rich Protein Is a Potential New Vitamin K Target in Cancer: Evidences for a Direct GRP-Mineral Interaction

Gla-rich protein (GRP) was described in sturgeon as a new vitamin-K-dependent protein (VKDP) with a high density of Gla residues and associated with ectopic calcifications in humans. Although VKDPs function has been related with γ-carboxylation, the Gla status of GRP in humans is still unknown. Here...

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Detalhes bibliográficos
Main Authors: Viegas, Carla S. B., Herfs, Marjolein, Rafael, Marta S., Enriquez, José L., Teixeira, Alexandra, Luís, Inês M., van ‘t Hoofd, Cynthia M. R., João, Alexandre, Maria, Vera L., Cavaco, Sofia, Ferreira, Ana, Serra, Manuel, Theuwissen, Elke, Vermeer, Cees, Simes, Dina C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052551/
https://ncbi.nlm.nih.gov/pubmed/24949434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/340216
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