Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling

Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in part, to be induced by phosphate imbalance. T...

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Publicado en:Sci Rep
Autores principales: Willems, Brecht A., Furmanik, Malgorzata, Caron, Marjolein M. J., Chatrou, Martijn L. L., Kusters, Dennis H. M., Welting, Tim J. M., Stock, Michael, Rafael, Marta S., Viegas, Carla S. B., Simes, Dina C., Vermeer, Cees, Reutelingsperger, Chris P. M., Schurgers, Leon J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862840/
https://ncbi.nlm.nih.gov/pubmed/29563538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23353-y
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