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APOBEC3A/B deletion polymorphism and cancer risk

Activity of the apolipoprotein B mRNA editing enzyme, catalytic-polypeptide-like (APOBEC) enzymes has been linked to specific mutational processes in human cancer genomes. A germline APOBEC3A/B deletion polymorphism is associated with APOBEC-dependent mutational signatures, and the deletion allele h...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Gansmo, Liv B, Romundstad, Paal, Hveem, Kristian, Vatten, Lars, Nik-Zainal, Serena, Lønning, Per Eystein, Knappskog, Stian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862322/
https://ncbi.nlm.nih.gov/pubmed/29140415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx131
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