The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability

FK506 binding proteins (FKBPs) catalyze the interconversion of cis-trans proline conformers in proteins. Importantly, FK506 drugs have anti-cancer and neuroprotective properties, but the effectors and mechanisms underpinning these properties are not well understood because the cellular function(s) o...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Dilworth, David, Gudavicius, Geoff, Xu, Xiaoxue, Boyce, Andrew K J, O’Sullivan, Connor, Serpa, Jason J, Bilenky, Misha, Petrochenko, Evgeniy V, Borchers, Christoph H, Hirst, Martin, Swayne, Leigh Anne, Howard, Perry, Nelson, Christopher J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861405/
https://ncbi.nlm.nih.gov/pubmed/29361176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky008
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