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Noncatalytic Role of the FKBP52 Peptidyl-Prolyl Isomerase Domain in the Regulation of Steroid Hormone Signaling

Hormone-dependent transactivation by several of the steroid hormone receptors is potentiated by the Hsp90-associated cochaperone FKBP52, although not by the closely related FKBP51. Here we analyze the mechanisms of potentiation and the functional differences between FKBP51 and FKBP52. While both hav...

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Detalhes bibliográficos
Main Authors: Riggs, Daniel L., Cox, Marc B., Tardif, Heather L., Hessling, Martin, Buchner, Johannes, Smith, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169416/
https://ncbi.nlm.nih.gov/pubmed/17938211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00985-07
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