Noncatalytic Role of the FKBP52 Peptidyl-Prolyl Isomerase Domain in the Regulation of Steroid Hormone Signaling

Hormone-dependent transactivation by several of the steroid hormone receptors is potentiated by the Hsp90-associated cochaperone FKBP52, although not by the closely related FKBP51. Here we analyze the mechanisms of potentiation and the functional differences between FKBP51 and FKBP52. While both hav...

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Bibliographic Details
Main Authors: Riggs, Daniel L., Cox, Marc B., Tardif, Heather L., Hessling, Martin, Buchner, Johannes, Smith, David F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169416/
https://ncbi.nlm.nih.gov/pubmed/17938211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00985-07
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