Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening

Immunophilins, including FK506-binding proteins (FKBPs), are protein chaperones with peptidyl-prolyl isomerase (PPIase) activity. Initially identified as pharmacological receptors for immunosuppressants to regulate immune responses via isomerase independent mechanisms, FKBPs are most highly expresse...

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Autori principali: Shim, Sangwoo, Yuan, Joseph P., Kim, Ju Young, Zeng, Weizhong, Huang, Guo, Milshteyn, Aleksandr, Kern, Dorothee, Muallem, Shmuel, Ming, Guo-li, Worley, Paul F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786904/
https://ncbi.nlm.nih.gov/pubmed/19945390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.09.025
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