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Adapting Secretory Proteostasis and Function through the Unfolded Protein Response

Cells address challenges to protein folding in the secretory pathway by engaging endoplasmic reticulum (ER)-localized protective mechanisms that are collectively termed the unfolded protein response (UPR). By the action of the transmembrane signal transducers IRE1, PERK, and ATF6, the UPR induces ne...

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Pubblicato in:Curr Top Microbiol Immunol
Autori principali: Wong, Madeline Y., DiChiara, Andrew S., Suen, Patreece H., Chen, Kenny, Doan, Ngoc-Duc, Shoulders, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860992/
https://ncbi.nlm.nih.gov/pubmed/28929194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2017_56
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