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Targeting Defective Proteostasis in the Collagenopathies

The collagenopathies are a diverse group of diseases caused primarily by mutations in collagen genes. The resulting disruptions in collagen biogenesis can impair development, cause cellular dysfunction, and severely impact connective tissues. Most existing treatment options only address patient symp...

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Détails bibliographiques
Publié dans:Curr Opin Chem Biol
Auteurs principaux: Wong, Madeline Y., Shoulders, Matthew D.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588406/
https://ncbi.nlm.nih.gov/pubmed/31028939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.02.021
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