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Adapting Secretory Proteostasis and Function through the Unfolded Protein Response
Cells address challenges to protein folding in the secretory pathway by engaging endoplasmic reticulum (ER)-localized protective mechanisms that are collectively termed the unfolded protein response (UPR). By the action of the transmembrane signal transducers IRE1, PERK, and ATF6, the UPR induces ne...
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| Publicado no: | Curr Top Microbiol Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860992/ https://ncbi.nlm.nih.gov/pubmed/28929194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2017_56 |
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