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Mechanisms for non-mitotic activation of Aurora-A at cilia

Overexpression of the Aurora-A (AURKA) kinase is oncogenic in many tumors. Many studies of AURKA have focused on activities of this kinase in mitosis, and elucidated the mechanisms by which AURKA activity is induced at the G2/M boundary through interactions with proteins such as TPX2 and NEDD9. Thes...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Korobeynikov, Vladislav, Deneka, Alexander Y., Golemis, Erica A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860652/
https://ncbi.nlm.nih.gov/pubmed/28202658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160142
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