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Mechanisms for non-mitotic activation of Aurora-A at cilia
Overexpression of the Aurora-A (AURKA) kinase is oncogenic in many tumors. Many studies of AURKA have focused on activities of this kinase in mitosis, and elucidated the mechanisms by which AURKA activity is induced at the G2/M boundary through interactions with proteins such as TPX2 and NEDD9. Thes...
Gardado en:
| Publicado en: | Biochem Soc Trans |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860652/ https://ncbi.nlm.nih.gov/pubmed/28202658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160142 |
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