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Detecting presence of mutational signatures in cancer with confidence

MOTIVATION: Cancers arise as the result of somatically acquired changes in the DNA of cancer cells. However, in addition to the mutations that confer a growth advantage, cancer genomes accumulate a large number of somatic mutations resulting from normal DNA damage and repair processes as well as car...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Huang, Xiaoqing, Wojtowicz, Damian, Przytycka, Teresa M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860213/
https://ncbi.nlm.nih.gov/pubmed/29028923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx604
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