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Detecting presence of mutational signatures in cancer with confidence
MOTIVATION: Cancers arise as the result of somatically acquired changes in the DNA of cancer cells. However, in addition to the mutations that confer a growth advantage, cancer genomes accumulate a large number of somatic mutations resulting from normal DNA damage and repair processes as well as car...
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| Publicado en: | Bioinformatics |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860213/ https://ncbi.nlm.nih.gov/pubmed/29028923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx604 |
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