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CRISPR RNA-dependent binding and cleavage of endogenous RNAs by the Campylobacter jejuni Cas9
Cas9 nucleases naturally utilize CRISPR RNAs (crRNAs) to silence foreign double-stranded DNA. While recent work has shown that some Cas9 nucleases can also target RNA, RNA recognition has required nuclease modifications or accessory factors. Here, we show that the Campylobacter jejuni Cas9 (CjCas9)...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859949/ https://ncbi.nlm.nih.gov/pubmed/29499139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.032 |
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