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Deciphering, communicating, and engineering the CRISPR PAM

Clustered regularly interspaced short palindromic repeat (CRISPR) loci and their flanking CRISPR-associated (cas) genes make up RNA-guided, adaptive immune systems in prokaryotes whose effector proteins have become powerful tools for basic research and biotechnology. While the Cas effector proteins...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Autores principales: Leenay, Ryan T., Beisel, Chase L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235977/
https://ncbi.nlm.nih.gov/pubmed/27916599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.11.024
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