Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state

BACKGROUND: Obesity is associated with increased risk, poor prognosis and outcome of therapy, in various cancers. Obesity-associated factors or adipokines, especially leptin and resistin, are purported to promote growth, survival, proliferation, and invasiveness of cancer cells. However, the mechani...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Metab
Main Authors: Malvi, Parmanand, Chaube, Balkrishna, Singh, Shivendra Vikram, Mohammad, Naoshad, Vijayakumar, Maleppillil Vavachan, Singh, Snahlata, Chouhan, Surbhi, Bhat, Manoj Kumar
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Rapid Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859707/
https://ncbi.nlm.nih.gov/pubmed/29568521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-018-0176-5
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