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Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance

BACKGROUND: Obesity-related cellular, metabolic, and molecular alterations have been shown to increase cancer risk and tumor progression and are associated with poorer therapeutic outcome in cancer patients. However, the impact of obesity and weight-control interventions on the therapeutic response...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Malvi, Parmanand, Chaube, Balkrishna, Singh, Shivendra Vikram, Mohammad, Naoshad, Pandey, Vimal, Vijayakumar, Maleppillil Vavachan, Radhakrishnan, Revathy Meenatheril, Vanuopadath, Muralidharan, Nair, Sudarslal Sadasivan, Nair, Bipin Gopalakrishnan, Bhat, Manoj Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142287/
https://ncbi.nlm.nih.gov/pubmed/27980732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-016-0162-8
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