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Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex

Doxorubicin (DOX) is one of the preferred drugs for treating breast and liver cancers. However, its clinical application is limited due to severe side effects and the accompanying drug resistance. In this context, we investigated the effect on therapeutic efficacy of DOX by cholesterol depleting age...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mohammad, Naoshad, Vikram Singh, Shivendra, Malvi, Parmanand, Chaube, Balkrishna, Athavale, Dipti, Vanuopadath, Muralidharan, Nair, Sudarslal Sadasivan, Nair, Bipin, Bhat, Manoj Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493576/
https://ncbi.nlm.nih.gov/pubmed/26149967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11853
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