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Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex

Doxorubicin (DOX) is one of the preferred drugs for treating breast and liver cancers. However, its clinical application is limited due to severe side effects and the accompanying drug resistance. In this context, we investigated the effect on therapeutic efficacy of DOX by cholesterol depleting age...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Mohammad, Naoshad, Vikram Singh, Shivendra, Malvi, Parmanand, Chaube, Balkrishna, Athavale, Dipti, Vanuopadath, Muralidharan, Nair, Sudarslal Sadasivan, Nair, Bipin, Bhat, Manoj Kumar
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493576/
https://ncbi.nlm.nih.gov/pubmed/26149967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11853
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