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Base Excision Repair Variants in Cancer

Base excision repair (BER) is a key genome maintenance pathway that removes endogenously damaged DNA bases that arise in cells at very high levels on a daily basis. Failure to remove these damaged DNA bases leads to increased levels of mutagenesis and chromosomal instability, which have the potentia...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Marsden, Carolyn G., Dragon, Julie A., Wallace, Susan S., Sweasy, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859333/
https://ncbi.nlm.nih.gov/pubmed/28645367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.03.003
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