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Variant Base Excision Repair Proteins: Contributors to Genomic Instability

Cells sustain endogenous DNA damage at rates greater than 20,000 DNA lesions per cell per day. These damages occur largely as a result of the inherently unstable nature of DNA and the presence of reactive oxygen species within cells. The base excision repair system removes the majority of DNA lesion...

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Detalhes bibliográficos
Main Authors: Nemec, Antonia A., Wallace, Susan S., Sweasy, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254599/
https://ncbi.nlm.nih.gov/pubmed/20955798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.10.010
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