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Variant Base Excision Repair Proteins: Contributors to Genomic Instability
Cells sustain endogenous DNA damage at rates greater than 20,000 DNA lesions per cell per day. These damages occur largely as a result of the inherently unstable nature of DNA and the presence of reactive oxygen species within cells. The base excision repair system removes the majority of DNA lesion...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254599/ https://ncbi.nlm.nih.gov/pubmed/20955798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.10.010 |
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