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Mitotic progression following DNA damage enables pattern recognition within micronuclei

Inflammatory gene expression following genotoxic cancer therapy is well documented, yet the events underlying its induction remain poorly understood. Inflammatory cytokines modify the tumor microenvironment by recruiting immune cells and are critical for both local and systemic (abscopal) tumor resp...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Harding, Shane M, Benci, Joseph L, Irianto, Jerome, Discher, Dennis E, Minn, Andy J, Greenberg, Roger A
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857357/
https://ncbi.nlm.nih.gov/pubmed/28759889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23470
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