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Alerting the immune system to DNA damage: micronuclei as mediators
Healthy cells experience thousands of DNA lesions per day during normal cellular metabolism, and ionizing radiation and chemotherapeutic drugs rely on DNA damage to kill cancer cells. In response to such lesions, the DNA damage response (DDR) activates cell-cycle checkpoints, initiates DNA repair me...
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| Publicado no: | Essays Biochem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7588664/ https://ncbi.nlm.nih.gov/pubmed/32844183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20200016 |
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