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Cell Cycle Checkpoints Cooperate to Suppress DNA and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses
The DNA-dependent pattern recognition receptor, cGAS (cyclic GMP-AMP synthase), mediates communication between the DNA damage and the immune responses. Mitotic chromosome missegregation stimulates cGAS activity; however, it is unclear whether progression through mitosis is required for cancercell-in...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530826/ https://ncbi.nlm.nih.gov/pubmed/32877684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108080 |
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