Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals

Animal models of Alzheimer’s disease (AD) have suggested that tau pathology propagation, facilitated by amyloid pathology, may occur along connected pathways. To investigate these ideas in humans, we combined amyloid scans with longitudinal data on white matter connectivity, hippocampal volume, tau...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Jacobs, Heidi I.L., Hedden, Trey, Schultz, Aaron P., Sepulcre, Jorge, Perea, Rodrigo D., Amariglio, Rebecca E., Papp, Kathryn V., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857215/
https://ncbi.nlm.nih.gov/pubmed/29403032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0070-z
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