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PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells
The spindle assembly checkpoint (SAC) acts as a molecular safeguard in ensuring faithful chromosome transmission during mitosis, which is regulated by a complex interplay between phosphatases and kinases including PLK1. Adenomatous polyposis coli (APC) germline mutations cause aneuploidy and are res...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856809/ https://ncbi.nlm.nih.gov/pubmed/29549256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03494-4 |
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