Mitotic arrest and slippage induced by pharmacological inhibition of Polo‐like kinase 1

Exposure to drugs that interfere with microtubule dynamics block cell cycle progression at mitosis by prolonged activation of the spindle assembly checkpoint (SAC). Cells can evade mitotic arrest and proceed to interphase without chromosome segregation by a process termed mitotic slippage that invol...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Raab, Monika, Krämer, Andrea, Hehlgans, Stephanie, Sanhaji, Mourad, Kurunci-Csacsko, Elisabeth, Dötsch, Christina, Bug, Gesine, Ottmann, Oliver, Becker, Sven, Pachl, Fiona, Kuster, Bernhard, Strebhardt, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528686/
https://ncbi.nlm.nih.gov/pubmed/25169932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.020
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