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Mitotic arrest and slippage induced by pharmacological inhibition of Polo‐like kinase 1

Exposure to drugs that interfere with microtubule dynamics block cell cycle progression at mitosis by prolonged activation of the spindle assembly checkpoint (SAC). Cells can evade mitotic arrest and proceed to interphase without chromosome segregation by a process termed mitotic slippage that invol...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Raab, Monika, Krämer, Andrea, Hehlgans, Stephanie, Sanhaji, Mourad, Kurunci-Csacsko, Elisabeth, Dötsch, Christina, Bug, Gesine, Ottmann, Oliver, Becker, Sven, Pachl, Fiona, Kuster, Bernhard, Strebhardt, Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528686/
https://ncbi.nlm.nih.gov/pubmed/25169932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.020
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