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Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8
Upon interaction of the CD95 receptor with its ligand, sequential association of the adaptor molecule FADD (MORT1), pro-forms of caspases-8/10, and the caspase-8/10 regulator c-FLIP leads to the formation of a death-inducing signaling complex. Here, we identify polo-like kinase (Plk) 3 as a new inte...
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Publicado no: | Cell Res |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973331/ https://ncbi.nlm.nih.gov/pubmed/27325299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.78 |
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