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Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium

Prostate cancer (PCa) is an androgen dependent disease that can be treated by androgen ablation therapy, and clinical trials are under way to prevent PCa through the reduction of androgen receptor (AR) activity. However, there are no animal models of AR-mediated prostatic neoplasia, and it remains u...

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Autors principals: Stanbrough, Michael, Leav, Irwin, Kwan, Paul W. L., Bubley, Glenn J., Balk, Steven P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58558/
https://ncbi.nlm.nih.gov/pubmed/11535819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191235898
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