Nalaganje...
Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice
Transgenic mice expressing human insulin-like growth factor 1 (IGF-1) in basal epithelial cells of prostate have been characterized. Transgene expression led to activation of the IGF-1 receptor and spontaneous tumorigenesis in prostate epithelium. Hyperplasia was evident in these mice by 2–3 months...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16261/ https://ncbi.nlm.nih.gov/pubmed/10737798 |
| Oznake: |
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