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Mutation Profiling Indicates High Grade Prostatic Intraepithelial Neoplasia as Distant Precursors of Adjacent Invasive Prostatic Adenocarcinoma

INTRODUCTION: High Grade Prostatic Intraepithelial Neoplasia (HGPIN) is the putative precursor lesion to prostatic adenocarcinoma (PCa), but the precise relationship between HGPIN and PCa remains unclear. METHODS: We performed a molecular case study in which we studied mutation profiles of six tumor...

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Détails bibliographiques
Publié dans:Prostate
Auteurs principaux: Gerrin, Sean J., Sowalsky, Adam G., Balk, Steven P., Ye, Huihui
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507580/
https://ncbi.nlm.nih.gov/pubmed/27272561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23212
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