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Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium

Prostate cancer (PCa) is an androgen dependent disease that can be treated by androgen ablation therapy, and clinical trials are under way to prevent PCa through the reduction of androgen receptor (AR) activity. However, there are no animal models of AR-mediated prostatic neoplasia, and it remains u...

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Autori principali: Stanbrough, Michael, Leav, Irwin, Kwan, Paul W. L., Bubley, Glenn J., Balk, Steven P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC58558/
https://ncbi.nlm.nih.gov/pubmed/11535819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191235898
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