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Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine
We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-γ responses were detected by enzyme-linked immunospot (ELISPOT) assays in all subjects to multiple 9- to 23-aa peptid...
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| Autori principali: | , , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58557/ https://ncbi.nlm.nih.gov/pubmed/11526203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181123498 |
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