Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8(+)-T-Cell Populations

The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding the Plasmodium yoelii circumsporozoite protein (PyCSP) and murine granulocyte-macrophage colony-stim...

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Detalhes bibliográficos
Main Authors: Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J., Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128102/
https://ncbi.nlm.nih.gov/pubmed/12065488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3493-3499.2002
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