A Small Peptide (CEL-1000) Derived from the β-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent Manner

CEL-1000 (DGQEEKAGVVSTGLIGGG) is a novel potential preventative and therapeutic agent. We report that CEL-1000 confers a high degree of protection against Plasmodium sporozoite challenge in a murine model of malaria, as shown by the total absence of blood stage infection following challenge with 100...

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Detalhes bibliográficos
Main Authors: Charoenvit, Yupin, Brice, Gary T., Bacon, David, Majam, Victoria, Williams, Jackie, Abot, Esteban, Ganeshan, Harini, Sedegah, Martha, Doolan, Denise L., Carucci, Daniel J., Zimmerman, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434180/
https://ncbi.nlm.nih.gov/pubmed/15215094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2455-2463.2004
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