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Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine

We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-γ responses were detected by enzyme-linked immunospot (ELISPOT) assays in all subjects to multiple 9- to 23-aa peptid...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon, Hoffman, Stephen L.
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC58557/
https://ncbi.nlm.nih.gov/pubmed/11526203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181123498
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