Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine

We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-γ responses were detected by enzyme-linked immunospot (ELISPOT) assays in all subjects to multiple 9- to 23-aa peptid...

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Dades bibliogràfiques
Autors principals: Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon, Hoffman, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58557/
https://ncbi.nlm.nih.gov/pubmed/11526203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181123498
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