Simultaneous Induction of Multiple Antigen-Specific Cytotoxic T Lymphocytes in Nonhuman Primates by Immunization with a Mixture of Four Plasmodium falciparum DNA Plasmids

CD8(+) T cells have been implicated as critical effector cells in protective immunity against malaria parasites developing within hepatocytes. A vaccine that protects against malaria by inducing CD8(+) T cells will probably have to include multiple epitopes on the same protein or different proteins,...

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Detalhes bibliográficos
Main Authors: Wang, Ruobing, Doolan, Denise L., Charoenvit, Yupin, Hedstrom, Richard C., Gardner, Malcolm J., Hobart, Peter, Tine, John, Sedegah, Martha, Fallarme, Victoria, Sacci, John B., Kaur, Manjit, Klinman, Dennis M., Hoffman, Stephen L., Weiss, Walter R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108505/
https://ncbi.nlm.nih.gov/pubmed/9712767
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