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Enantioselective synthesis of cyclopenta[b]benzofurans via an organocatalytic intramolecular double cyclization

An enantioselective organocatalytic strategy, combining Brønsted base and N-heterocyclic carbene catalysis in a unique manner, is demonstrated for a concise construction of the privileged cyclopenta[b]benzofuran scaffold, present in many bioactive compounds having both academic and commercial intere...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Paz, Bruno Matos, Li, Yang, Thøgersen, Mathias Kirk, Jørgensen, Karl Anker
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855134/
https://ncbi.nlm.nih.gov/pubmed/29568457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03006a
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