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Enantioselective synthesis of cyclopenta[b]benzofurans via an organocatalytic intramolecular double cyclization

An enantioselective organocatalytic strategy, combining Brønsted base and N-heterocyclic carbene catalysis in a unique manner, is demonstrated for a concise construction of the privileged cyclopenta[b]benzofuran scaffold, present in many bioactive compounds having both academic and commercial intere...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Paz, Bruno Matos, Li, Yang, Thøgersen, Mathias Kirk, Jørgensen, Karl Anker
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855134/
https://ncbi.nlm.nih.gov/pubmed/29568457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03006a
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