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Efficient syntheses of (–)-crinine and (–)-aspidospermidine, and the formal synthesis of (–)-minfiensine by enantioselective intramolecular dearomative cyclization

Polycyclic alkaloids bearing all-carbon quaternary centers possess a diversity of biological activities and are challenging targets in natural product synthesis. The development of a general and asymmetric catalytic method applicable to the efficient syntheses of a series of complex polycyclic alkal...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Du, Kang, Yang, He, Guo, Pan, Feng, Liang, Xu, Guangqing, Zhou, Qinghai, Chung, Lung Wa, Tang, Wenjun
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628388/
https://ncbi.nlm.nih.gov/pubmed/28989658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01859b
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