Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice

Pancreatic beta-cells are selectively destroyed by the host immune system in type 1 diabetes. Thus, drugs that preserve beta-cell mass and/or function have the potential to prevent or slow the progression of this disease. We recently reported that the use-dependent sodium channel blocker, carbamazep...

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Udgivet i:Sci Rep
Main Authors: Lee, Jason T. C., Shanina, Iryna, Chu, Yung Ning, Horwitz, Marc S., Johnson, James D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854601/
https://ncbi.nlm.nih.gov/pubmed/29545618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23026-w
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