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Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy
Autoimmune destruction of the pancreatic islets in Type 1 diabetes is mediated by both increased proinflammatory (Teff) and decreased regulatory (Treg) T lymphocytes resulting in a significant decrease in the Treg:Teff ratio. The non-obese diabetic (NOD) mouse is an excellent in vivo model for testi...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692265/ https://ncbi.nlm.nih.gov/pubmed/26674203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145179 |
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