Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice

OBJECTIVE: The T helper 17 (Th17) population, a subset of CD4-positive T-cells that secrete interleukin (IL)-17, has been implicated in autoimmune diseases, including multiple sclerosis and lupus. Therapeutic agents that target the Th17 effector molecule IL-17 or directly inhibit the Th17 population...

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Autores principales: Emamaullee, Juliet A., Davis, Joy, Merani, Shaheed, Toso, Christian, Elliott, John F., Thiesen, Aducio, Shapiro, A.M. James
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2009
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682686/
https://ncbi.nlm.nih.gov/pubmed/19289457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1113
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