Th1 and Th17 Immunocompetence in Humanized NOD/SCID/γC-KO mice

We evaluated the immunocompetence of human T cells in humanized NOD-scid IL2r-γ-null (Hu—NSG) mice bearing a human thymic organoid, after multilinegage reconstitution with isogeneic human leukocytes. Delayed type hypersensitivity (DTH) response was assessed by a direct footpad challenge of the immun...

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Autori principali: Rajesh, Deepika, Zhou, Ying, Jankowska-Gan, Ewa, Ronneburg, Drew Allan, Dart, Melanie M, Torrealba, Jose, Burlingham, William J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875879/
https://ncbi.nlm.nih.gov/pubmed/20298731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2010.02.019
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