Transfer of tolerance to collagen type V suppresses Th-17 lymphocyte mediated acute lung transplant rejection

BACKGROUND: Rat lung allograft rejection is mediated by collagen type V (col(V)) specific Th17 cells. Adoptive transfer of these cells is sufficient to induce rejection pathology in isografts, whereas tolerance to col(V) suppresses allograft rejection. We therefore tested if regulatory T cells from...

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Autori principali: Braun, Ruedi K., Molitor-Dart, Melanie, Wigfield, Christopher, Xiang, Zhuzai, Fain, Sean B., Jankowska-Gan, Ewa, Seroogy, Christine M., Burlingham, William J., Wilkes, David S., Brand, David D., Torrealba, Jose, Love, Robert B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804859/
https://ncbi.nlm.nih.gov/pubmed/20029330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181bcde7b
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