Leukocyte-Associated Ig-like Receptor 1 Inhibits T(h)1 Responses but Is Required for Natural and Induced Monocyte-Dependent T(h)17 Responses

Leukocyte-associated Ig-like receptor 1 (LAIR1) is an ITIM-bearing collagen receptor expressed by leukocytes and is implicated in immune suppression. However, using a divalent soluble LAIR1/Fc recombinant protein to block interaction of cell surface LAIR1 with matrix collagen, we found that whereas...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Agashe, Vrushali V., Jankowska-Gan, Ewa, Keller, Melissa, Sullivan, Jeremy A., Haynes, Lynn D., Kernien, John F., Torrealba, Jose R., Roenneburg, Drew, Dart, Melanie, Colonna, Marco, Wilkes, David S., Burlingham, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039397/
https://ncbi.nlm.nih.gov/pubmed/29884698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701753
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