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Immunomodulation of Antigen Presenting Cells Promotes Natural Regulatory T Cells That Prevent Autoimmune Diabetes in NOD Mice

Progression towards type 1 diabetes (T1D) in susceptible patients is linked to a progressive decline in the capacity of regulatory T cells (Treg) to maintain tolerance. As such, therapies aimed at redressing the failing Treg compartment have been the subject of intense investigation. Treg dysfunctio...

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Bibliografski detalji
Glavni autori: Richer, Martin J., Lavallée, Danielle J., Shanina, Iryna, Horwitz, Marc S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280284/
https://ncbi.nlm.nih.gov/pubmed/22355341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031153
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